مجله مطالعات ناتوانی
سال سوم شماره 2 (پاییز 1392)

In the studies of genomics, it is essential to select a small number of single nucleotide polymorphisms (SNPs). That is more significant than the others for the association studies of disease susceptibility. Data mining technology provides an important means for extracting valuable medical rules hidden in medical data and acts as an important role in disease prediction and clinical diagnosis. In this study, our goal was to compare two machine learning methods using genetic factor and single nucleotide polymorphisms. In order to perform the data analysis, a total of 141 patients and 83 controls in the genetic's section of Shahid Rajaee's heart center. The blood samples to draw conclusions about the LDLR and PCSK9 gene's SNPs was used. Also, the random forest and CART was used in order to discover the relationship between CAD and SNPs. These models were assessed by using four criteria including: sensitivity, specificity, precision and error. Data analysis was performed by SPSS (16.0) and R (2.15.0). CART had the better performance than Random Forest. Sensitivity, specificity, precision and error were 0.893, 0.506, 0.250 and 0.754 relatively. We introduced an algorithm to classify the high risk and low risk cases.CART is suggested in order to assess the relationship between CAD and SNPs.

The purpose of this study was determinning /identifying the barriers to disabled peoples employment and providing rehabilitation policy makers guidelines to confront these barriers.Twenty people with physical disabilities, ten people of their families and ten Rehabilitation managers/personnel who deal with the disabled people were chosen. Barriers of employment were identified via interview. Bycontent analysis of the interviews, a questionnaire was regulated and questionnaire distributed among 437 people with physicaldisabilities who were randomly selected. In order to determine the validity of the questionnaire Rosenberg self-esteem scale with barriers to employment questionnaire distributed and the validity coefficient was 0.71(p<0.05). To evaluate the reliability of questionnaire, Cronbach’s alpha was used andCronbach’s alpha coefficients economic barriers (0.74), attitud barriers (0.69), educational barriers (0.77), Laws barriers (0.76) and physical barriers (0.71) obtained. 43as an impediment to the employment of people with motor disabilities were identified and closely related to the concepts of the material, in the form of five factors including economic barriers, attitudinal, educational, environmental and legal were classified. Confirmatoryf actor analysisrevealed that 43of these 5 factors are composed of material and all have significant effects on the factors related to them. All these factors were significant in the level (p<0.05). The attitudinal barriers was the least important and the physical and enviromental barriers was main and the gender of peoples is minor factors and inappropriate streets and sidewalks and buildings. The negative attitude of distrust towards the empowerment of persons with disabilities was importance factors. According to the results, it was found that people with motor disabilities faces barriers in employment with five kind of (economic, attitud, education, Laws, physical) barriers. This study discuss solutions for eliminating these barriers and provide guidance for rehabilitation policy makers.

The aim of this study was to determine family function and family structure of parents who have son with disability based on the Circumplex Model of Marital and Family system in Tehran in 1390. In a descriptive study, 200 parents (100 families) who had a son with disability, from elementary public school in Tehran was selected via multi-stage cluster sampling. Each parent completed the two parts questionnaire, demographic variables and family Adaptability and Cohesion Evaluation Scales III Olson & et al 1985 (FACESIII). Adaptability and cohesion dimension of family function and family structure perceived with parents were determined upon circumplex model. Mothers rated their families more cohesive and less adaptive than fathers. Mother’s cohesion was (40.12) while father’s cohesion was (39.66), adaptability of mothers was (27.14) and adaptability of fathers was (27.89). Cohesion and adaptability scores in mothers and fathers were not statistically significant. It means understanding of both mothers and fathers about cohesion and adaptability is similar to each others. Most of the family structure perceived with parents were balanced and mid-range. There were no relationship between family structure and family function with type of disability of children. Adequate adaptability and cohesion in family is one of the most criteria for the healthy family function in the circumplex model and many other structural theories of family. Scale and model of circumplex model can be useful for family function and family structure assessment, cure planning and evaluation of outcome of family therapy.

The aim of present study was to review the efficacy of the religious trainings based on Quran and Islamic traditions on the meaningfulness of elderly men’s life. The study design was quasi experimental post‒test, pre‒test with control group. The sampling method was accessible sampling based on the goal. In the way that from 150 elderly men living in Kahrizak center who had participated voluntary and had the including criteria were selected. From these number, 32 people were selected accidentally and divided accidental in two groups: intervention and control groups. The Intervention group had 8sessions of RCT, http://www.win2farsi.comtwice a week and each session was 90 minutes. Meaningfulness 10‒question Questionnaire was administered to the control group and intervention group before and after intervention. Analysis of covariance were used to compare two group data. Analysis of covariance indicated that the efficacy of religious based training on life meaning and its sections in intervention group rather than before and after intervention is significantly meaningful (p<0.001), but this efficacy is not meaningful in comparison with control group(p >0.005). It seems that religious components training can increase elderly’s hope, and finally their life will be meaningful. But, instead of only training, paying more attention to assignment is needed for more significant effectiveness; this issue should be considered in therapy manual.

The purpose of this study was finding the effect of 8-week rehabilitation program on pain reduction and improving nerve conduction in patient exposed with carpal tunnel syndrome. 15 person of Bank workers in Ilam city were participated in the study. These people exposed with carpal tunnel syndrome (18 wrist) that divided randomly in two group. The tools involved personal information, Visual Analog Scale (VAS test), and electro diagnostic test. Rehabilitation protocol was informed by experimental group in 8 week. Experimental group performed daily and regularly this program in duration work hours in 6 period (each period last 10 minutes and in total 60 minutes). Control group didnt performed any program in rehabilitation stage. The result of this study indicated that in post test, pain rate in duration activity (p=0.001) and parastesy (p=0.018) in experimental group was significantly lower than control group. But significant difference didnt been observed between two groups in terms of pain rate (p>0.05). Also about nerve conduction parameters, the result showed that in post test there was significant difference between two groups in terms of sensory and motor nerve conduction velocity, wave peak and distal latency (p<0.05). According to the results, performing high program has significant effect on pain reduction, hand parastesy and improvement of nerve conduction.

Mixed methods research is viewed as the third methodological movement that has emerged in response to the limitation use of current (qualitative or quantitative) methods. In recent years, use of these methods is increasing in most fields like health care sciences and especially in nursing. The purpose of this article is to provide researchers learn more about mixed methods studies and introduction to current typologies that can help researchers in choosing optimum mixed methods research design. Purposive library search, electronic resources and data bases was used to gather information to be organized and presented here. The findings of this study have been presented in the form of introducing a mixed methods research, typology and tips for choosing the suitable design. There are various designs of mixed studies. Researchers need to be aware of the mixed method typologies and factors affecting the choice of a suitable design.